Epidural clonidine utilized being an adjunct to regional anesthetics has three different mechanisms of action. 1st, the stimulation of alpha-two-receptors in the dorsal horn minimizes suffering transmission. Next, clonidine could cause nearby vasoconstriction that restrictions vascular elimination of local epidural anesthetics. On the list of theories about the mechanism https://www.proleviate.com/post/the-new-pain-killer-conolidine